Data for "Carioscia, S. A., Biddanda, A., et al. (2025). Common variation in meiosis genes shapes human recombination phenotypes and aneuploidy risk."

This directory contains summarized data for analysis of aneuploidy from 139,416 embryos from 22,850 sets of parents. Tables contained within the directory are (each sub-directory contains its own README): aneuploidy_calls: tables with posterior probabilities and aneuploidy calls for all individuals based on karyoHMM (autosomes, sex-chromosomes & segmental) metadata: metadata table including casefile ID and biological parent ages recombination: tables with output of called crossover recombination events as described in the methods (including parental origins) gwas_sumstats: GWAS summary statistics for maternal meiotic aneuploidy and sex-stratified recombination traits twas_sumstats: TWAS summary statistics based on predicted expression in GTEx with p-values combined using ACAT Contact Rajiv McCoy: [e-mail]