The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3
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The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3 Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*CP*AP*TP*CP*GP*AP*TP*CP*GP*CP*AP*GP*CP*TP*TP*CP*AP*GP*AP*TP*AP*GP*G)-3'), ... Authors: Thomsen, M, Neudegger, T, Thieulin-Pardo, G, Blaesse, M, Costanzi, E, Steinbacher, S, Plotnikov, N.V, Dominguez, C, Iyer, R.R, Wilkinson, H.A, Monteagudo, E, Haque, T.S, Prasad, B.C, Finley, M, Boudet, J, Vogt, T.F, Felsenfeld, D.P. Deposit date: 2023-12-01 Release date: 2025-06-11 Last modified: 2025-07-09 Method: X-RAY DIFFRACTION (2.33 Å) Cite: The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3 To Be Published
结合DNA的人类MutSβ(MSH2/MSH3)在经典错配结合构象下的晶体结构,其中MSH2与MSH3结合了腺苷-5'-二磷酸(ADENOSINE-5'-DIPHOSPHATE)。描述符:1,2-乙二醇(1,2-ETHANEDIOL)、腺苷-5'-二磷酸、DNA(5'-D(*TP*CP*AP*TP*CP*GP*AP*TP*CP*GP*CP*AP*GP*CP*TP*TP*CP*AP*GP*AP*TP*AP*GP*G)-3'),…… 作者:汤姆森(Thomsen, M)、诺伊德格(Neudegger, T)、蒂厄兰-帕尔多(Thieulin-Pardo, G)、布莱瑟(Blaesse, M)、康齐(Costanzi, E)、施泰因巴赫(Steinbacher, S)、普洛特尼科夫(Plotnikov, N.V)、多明格斯(Dominguez, C)、艾耶(Iyer, R.R)、威尔金森(Wilkinson, H.A)、蒙塔古多(Monteagudo, E)、哈克(Haque, T.S)、普拉萨德(Prasad, B.C)、芬利(Finley, M)、布德(Boudet, J)、沃格特(Vogt, T.F)、费尔斯菲尔德(Felsenfeld, D.P.)。沉积日期:2023年12月1日;发布日期:2025年6月11日;最后修改日期:2025年7月9日。实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.33埃。引用:结合DNA的人类MutSβ(MSH2/MSH3)在经典错配结合构象下的晶体结构,其中MSH2与MSH3结合了ADP,待发表(To Be Published)



