Interaction of the rectal microbiome with SIV vaccine-induced immune responses and protective efficacy in rhesus macaques

The study evaluated immunogenicity and protective efficacy of mucosal priming with replication-competent Adenovirus-SIV recombinants following by systemic boosting with ALVAC-SIV recombinants plus SIV envelope protein or with DNA encoding SIV genes plus SIV envelope protein in rhesus macaques. This submission was on behalf of Dr. Marjorie Robert-Guroff Contact: Marjorie Robert-Guroff. This submission was powered by METAGENOTE (https://metagenote.niaid.nih.gov).