Summary of phenotypes obtained in organotypic cultures.
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↓: gene downregulated in the Pax6Sey/Seymms; ≈: gene expressed similarly in the wt and the Pax6Sey/Seymms; ↑: gene upregulated in the Pax6Sey/Seymms; ?: overexpression via TRE responder constructs; : knockdown via siRNAs or shRNA constructs, ablation of expression domain, or functional knockdown by fusion to the repressor domain of engrailed (EnR); nXII: hypoglossal nucleus;Genes showing no or only minor mms migration phenotypes after over-expression:Apbb2, Calpactin LC, Diras2, Gata3, Gli1, Hermes, Hip1, Internexin, Irx2, Irx6, Isl2, L1Cam, Math5, Nell2, Neurod6, Nfl, Ngn1, Ngn2, Nrp1, Olf1, Persyn, Pou6f1, RgmA, RgmB, Sema 7a, Stathmin, Syt4, Syt13.
创建时间:
2015-12-02



