MODOMICS

MODOMICS is the first comprehensive database system for biology of RNA modification. It integrates information about the chemical structure of modified nucleosides, their localization in RNA sequences, pathways of their biosynthesis and enzymes that carry out the respective reactions (together with their protein cofactors). Also included are the protein sequences, the structure data (if available), selected references from scientific literature, and links to other databases allowing to obtain comprehensive information about individual modified residues and proteins involved in their biosynthesis.MODOMICS是首个面向RNA修饰生物学的综合性数据库系统。该库整合了修饰核苷的化学结构、其在RNA序列中的定位、其生物合成途径以及催化对应反应的酶（连同其蛋白质辅因子）的相关信息。此外，该数据库还收录了蛋白质序列、结构数据（若有）、精选的科学文献参考文献，以及可用于获取单个修饰残基及其生物合成相关蛋白质综合信息的其他数据库链接。

搜集汇总

背景与挑战

背景概述

MODOMICS是一个专注于RNA修饰的综合性数据库。它整合了修饰核糖核苷的化学结构、生物合成途径、RNA序列中修饰残基的定位以及相关修饰酶的信息。该数据库旨在为RNA修饰研究提供全面的数据资源。