MUC1, MUC4, Stn, TN dataset in cervical cancer

The photomicrographs are images of immunohistochemically stained cervical cancer and lymph node metastases. The specimens were prospectively collected from patients enrolled in the Gynecologic Oncology Group (GOG) clinical trial GOG0221: Glycoprotein and glycan profiling in patients with locally advanced cervical cancer (Stage IB2, IIA > 4 cm, IIB to IVA) undergoing pelvic and para-aortic (abdominal) lymphadenectomy (clinicaltrials.gov:NCT00460356). Sections of the specimens immunohistochemically stained for mucin 1 and 4 proteins (MUC1 and MUC4, respectively) and Sialyl Tn (STn) and Tn antigens were reviewed by experienced gynecologic pathologists and areas of interest for photomicrography were selected by the first two authors of this brief (R.R. and R.C.). Representative images for all immunohistochemical stains showing their expression patterns as well as positive and negative controls were shown and described.