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Activation of STAT3 through SRC and EGFR Drives Resistance to a Mitotic Kinesin Inhibitor in Glioblastoma

NIAID Data Ecosystem2026-03-14 收录

胶质母细胞瘤耐药性

STAT3信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE193180 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-01-24

胶质母细胞瘤耐药性

靶向治疗信号通路

The outcome for patients afflicted with glioblastoma (GBM), the most common and malignant of primary brain tumors in adults, has changed little despite decades of clinical, translational, and basic re

NIAID Data Ecosystem70

A new mixed-ligand Co(II) coordination polymer: treatment activity on ulcerative colitis by inhibiting the JAK2/STAT3 signaling pathway in the colonic epithelial cells

STAT3信号通路

结肠炎治疗

In the current study, a novel mixed-ligand coordination polymer, {[Co(L)(dpe)]·(ClO 4 )} ( 1 ) (H 2 LCl = 3-carboxy-1-(3-carboxybenzyl)pyridin-1-ium, dpe = (E)-1,2-di(pyridin-4-

DataCite Commons2024-02-15 更新60

Asialoglycoprotein receptor 1 functions as a tumor suppressor in liver cancer via inhibition of STAT3

肝癌抑癌机制

STAT3信号通路

Liver cancer is characterized by aggressive growth and high mortality. Asialoglycoprotein receptor 1 (ASGR1), which is expressed almost exclusively in liver cells, is reduced in liver cancer. However,

NIAID Data Ecosystem40

Additional file 12 of MAFF alleviates hepatic ischemia–reperfusion injury by regulating the CLCF1/STAT3 signaling pathway

STAT3信号通路

Additional File 12.

Figshare2025-04-02 更新60

Thrombin exerts an inflammatory role in chondrocytes through activating the MEK-Erk1/2-Stat3 signaling pathway.

STAT3信号通路

细胞骨架调控

Rat chondrocytes were divided into control group (RP), thrombin group (RPT), and thrombin plus inhibitor group (RPTi). The differential genes were identified by RNA-sequencing, and verified by western

NIAID Data Ecosystem40

Activation of STAT3 through SRC and EGFR Drives Resistance to a Mitotic Kinesin Inhibitor in Glioblastoma

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