Effects of storage time and tissue volume in the yield and quality of RNA, and expression level of RNU6, from formalin-fixed paraffin-embedded prostate cancer tissues

Background: Molecular analyses of tumor RNA expression have become widely used both for research and clinical purposes. Tumoral tissue preservation is a critical step to ensure accuracy of molecular-based diagnostics, for which, formalin-fixed and paraffin-embedded (FFPE) tissues represent a valuable source of clinical samples. MicroRNAs are ideal...