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Cryo-EM structure of the mouse TRPM8 channel in complex with the antagonist AMG2850

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Protein Data Bank Japan2024-10-23 更新2026-06-30 收录
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https://pdbj.org/mine/summary/9b6f
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Cryo-EM structure of the mouse TRPM8 channel in complex with the antagonist AMG2850 Descriptor: (8R)-8-[4-(trifluoromethyl)phenyl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]-5,8-dihydro-1,7-naphthyridine-7(6H)-carboxamide, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 8 Authors: Yin, Y, Park, C.-G, Zhang, F, Fedor, J, Feng, S, Suo, Y, Im, W, Lee, S.-Y. Deposit date: 2024-03-25 Release date: 2024-08-21 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8. Sci Adv, 10, 2024
创建时间:
2024-03-25
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