Regioselective Synthesis of 3-Arylamino- and 5-Arylaminoisoxazoles from Enaminones
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https://figshare.com/articles/dataset/Regioselective_Synthesis_of_3_Arylamino_and_5_Arylaminoisoxazoles_from_Enaminones/2560738
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资源简介:
A highly regioselective synthesis of 3-arylamino- and 5-arylaminoisoxazoles from enaminones based on reaction condition selection is reported. 3-Arylaminoisoxazoles were produced by treating enaminones with aqueous hydroxylamine in DMF at 100 °C, whereas 5-arylaminoisoxazoles were synthesized by subjecting enaminones to aqueous hydroxylamine in the presence of KOH and TBAB in water under reflux. A mechanism for the regioselective synthesis of 3-arylamino- and 5-arylaminoisoxazoles is proposed.
创建时间:
2016-02-22



