Gene expression profile at single cell level of adrenal glands from the Tmem127 wild type (WT) and knocked out (KO) mice. Gene expression profile at single cell level of adrenal glands from the Tmem127 wild type (WT) and knocked out (KO) mice

Tmem127 is a tumor suppressor gene that has been linked to inherited susceptibility to pheochromocytomas. We used single nuclei RNA sequencing (snRNA-seq) to explore the cellular role of Tmem127. Overall design: Nuclei from 6 pairs frozen adrenal glands were extracted and isolated by Fluorescence-activated cell sorting (FACS) according to the DPI signal and analyzed using snRNAseq.