CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation II. CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation II

CTCF绝缘机制

Although the chromatin regulator CTCF is enriched at genes escaping from X-chromosome inactivation (XCI), molecular mechanisms remain elusive. We examined CTCF and epigenetic features at escape genes

NIAID Data Ecosystem40

Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos [RNA-seq]. Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos [RNA-seq]

Hox基因时序激活

CTCF绝缘机制

During development, Hox genes are activated in a time sequence following their relative positions on their clusters, leading to the proper identities of structures along the rostral to caudal axis. To

NIAID Data Ecosystem40

CRISPR and biochemical screens Identify MAZ as a co-factor in CTCF-mediated insulation at Hox Clusters [CUT&RUN_set1]

CTCF绝缘机制

Hox基因簇调控

In this experiment, we sought to identify how the distribution of CTCF, RAD21, H3K27me3 and H3K4me3 change in WT and double-positive MAZ HoxA(Δ5|6) cervical motor neurons (MNs). Examination of CTCF, R

NIAID Data Ecosystem20

CRISPR and biochemical screens Identify MAZ as a co-factor in CTCF-mediated insulation at Hox Clusters [ChIP-seq_set7]

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CRISPR and biochemical screens Identify MAZ as a co-factor in CTCF-mediated insulation at Hox Clusters [ChIP-seq_set7]

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