The effect of IFNAR1 blockade on Tfh-cell production of IL-21 and IFN-γ loci
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE156575
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To determine if the effect of IFNAR1 blockade on Tfh-cell production of IL-21 and IFN-γ was a consequence of altered chromatin accessibility, we used ATAC-seq to characterize their gene loci. Sorted Tfh cells (CD4+CD44+GITR-PSGL-1loCXCR5hiPD-1hi) from 5-month old B6/Sle1.Yaa mice treated twice a week for 4 weeks with either anti-IFNA1 or anti-rat IgG
创建时间:
2021-03-01



