Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors
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Discovery of Hydroxy Pyrimidine Factor IXa Inhibitors Descriptor: 4-{[5-hydroxy-6-(4-methylphenyl)pyrimidin-4-yl]amino}benzene-1-carboximidamide, CITRIC ACID, Coagulation factor IX, ... Authors: Jayne, C.L, Andreani, T, Chan, T, Chelliah, M.V, Clasby, M.C, Dwyer, M, Eagen, K.A, Fried, S, Greenlee, W.J, Guo, Z, Hawes, B, Hruza, A, Ingram, R, Keertikar, K.M, Neelamkavil, S, Reichert, P, Xia, Y, Chackalamannil, S. Deposit date: 2020-05-26 Release date: 2020-06-24 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.246 Å) Cite: Discovery of hydroxy pyrimidine Factor IXa inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
羟基嘧啶类凝血因子IXa（Factor IXa）抑制剂的发现 描述物：4-{[5-羟基-6-(4-甲基苯基)嘧啶-4-基]氨基}苯-1-甲脒、柠檬酸（CITRIC ACID）、凝血因子IX（Coagulation factor IX）等 作者：Jayne, C.L、Andreani, T、Chan, T、Chelliah, M.V、Clasby, M.C、Dwyer, M、Eagen, K.A、Fried, S、Greenlee, W.J、Guo, Z、Hawes, B、Hruza, A、Ingram, R、Keertikar, K.M、Neelamkavil, S、Reichert, P、Xia, Y、Chackalamannil, S 存放日期：2020-05-26 发布日期：2020-06-24 最后修改日期：2024-10-30 检测方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.246埃） 引用文献：《羟基嘧啶类凝血因子IXa抑制剂的发现》，《Bioorg.Med.Chem.Lett.》，第30卷，2020年
