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Long-read Transcriptome Sequencing Reveals Abundant Promoter Diversity in Distinct Molecular Subtypes of Gastric Cancer

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NIAID Data Ecosystem2026-03-12 收录
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Deregulated gene expression is a hallmark of cancer, however most studies to date have analyzed short-read RNA-sequencing data with inherent limitations. Here, we combined PacBio isoform sequencing (Iso-Seq) and Illumina paired-end short read RNA sequencing to comprehensively survey the transcriptome of gastric cancer (GC), a leading cause of global cancer mortality.

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2020-12-10
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