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Mechanisms of precise genome editing using oligonucleotide donors

NIAID Data Ecosystem2026-03-10 收录

数据链接：

https://figshare.com/articles/dataset/Mechanisms_of_precise_genome_editing_using_oligonucleotide_donors/5016422 数据链接链接失效反馈

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资源简介：

Sanger and NGS data for conversion tracts in HCT116, DLD-1 and RPE cells

应用场景：

创建时间：

2017-05-18

基因编辑机制

细胞应激反应

DNA damage activates a robust transcriptional stress response, but much less is known about how DNA damage impacts translation. The advent of genome editing with Cas9 has intensified interest in under

NIAID Data Ecosystem90

Mechanisms of precise genome editing using oligonucleotide donors. Homo sapiens

基因编辑机制

寡核苷酸供体技术

Supplemental Data for Mechanisms of precise genome editing using oligonucleotide donors

NIAID Data Ecosystem30

Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in a translocation state

CRISPR-Cas9

基因编辑机制

Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in a translocation state Descriptor: CRISPR-associated endonuclease Cas9, MAGNESIUM ION, Non-target DNA strand, ... Authors: Omura, S.N, N

Protein Data Bank Japan2026-04-29 更新20

Crystal structure of dCas9 in complex with sgRNA and DNA (CGA PAM)

CRISPR-Cas9

基因编辑机制

Crystal structure of dCas9 in complex with sgRNA and DNA (CGA PAM) Descriptor: CRISPR-associated endonuclease Cas9, non-target DNA, sgRNA, ... Authors: Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji

Protein Data Bank Japan2023-11-22 更新60

SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State I - pre-activation)

CRISPR-Cas结构生物学

基因编辑机制

SpCas9 with 17-bp R-loop containing 2 terminal mismatches (State I - pre-activation)

NIAID Data Ecosystem30