Supplementary Table S3 from The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma

XLSX file 261K, Supplementary Table S3. Mutations seen in patients with tumors at one time point. For patients with whole exome sequencing data on either pre-treatment (for early resistance cases) or after relapse (for acquired resistance cases), this table summarizes the complete set of non-synonymous mutations and short insertion/deletions called. Alterations in this table met the additional criteria of at least 30X coverage in the tumor and an allelic fraction of at least 0.05. Each column is a patient, each row is a gene, and each non-blank entry denotes the protein change that results from the mutation seen