Effects of AF3485 on leukotriene biosynthesis.
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A23187 (5 µM) stimulated-HL-60 cells were exposed to AF3485 (10 µM) for 30 min at 37°C, then LTB4 and LTC4 secretion was measured by EIA. Nordihydroguiaretic acid (NDGA) and (Phorbol 12-myristate 13-acetate) PMA were used as reference compounds. Inhibition values were obtained in 3 separate experiments.
创建时间：
2015-12-02
