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Single cell approaches define neural stem cell niches and identify microglial ligands that enhance precursor-mediated remyelination

NIAID Data Ecosystem2026-05-02 收录

神经干细胞生态位

髓鞘再生

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE266690 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-09-03

髓鞘再生

少突胶质细胞分化

Arrest of oligodendrocyte (OL) differentiation and remyelination following myelin damage in Multiple Sclerosis (MS) are associated with disease progression but the underlying mechanism are elusive. We

NIAID Data Ecosystem70

List of therapeutic antibodies from Mayo.

治疗性抗体

髓鞘再生

These antibodies were shipped from Mayo (Rochester, MI) to ASU (Phoenix, AZ) blinded, labeled only by the source (human or mouse) and the number (Antibody ID). The Code, Specificity in CNS and the Fun

NIAID Data Ecosystem60

Dor regulates alpha-KG metabolic pathways in mature oligodendrocytes to enhance myelination and reverse age-related remyelination decline [CUT&Tag]

髓鞘再生

少突胶质细胞

Impairment of oligodendrocyte (OL) myelinogenic potential, rather than inability of oligodendrocyte precursors to differentiate, is implicated in remyelination failure in demyelinating diseases such a

Alliance of Genome Resources50

CD140a+ human oligodendrocyte progenitor cells

少突胶质前体细胞

髓鞘再生

Glial progenitor cells (GPCs) pervade the human brain. These cells express gangliosides recognized by MAb A2B5, and some but not all can generate oligodendrocytes. Since some A2B5+ GPCs express PDGFa

NIAID Data Ecosystem60

Age-dependent decline of TET1-mediated DNA hydroxy-methylation impairs myelin regeneration after injury. Age-dependent decline of TET1-mediated DNA hydroxy-methylation impairs myelin regeneration after injury

髓鞘再生

DNA羟甲基化

Adult myelination is recognized as essential for brain function and response to injury and yet, its molecular understanding is mostly inferred from developmental studies. In this study, we identify DN

NIAID Data Ecosystem50

Single cell approaches define neural stem cell niches and identify microglial ligands that enhance precursor-mediated remyelination

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