Mapping snoRNA-target RNA interactions in an RNA binding protein-dependent manner with chimeric eCLIP [Ribo_Meth-seq]
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP533208
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资源简介：
To determine potential snoRNA-guided methylation in rRNA and snRNA in mESC, we performed RiboMeth-seq to quantify 2'-O-methylation levels. Overall design: 2'-O-methylation footprint in mouse ESCs was quantified by RiboMeth-seq. To identify modification sites guided by Snord89 and Snord101, we knocked down these snoRNAs with antisense oligonucleotides (ASOs) in differentiated 'induced' neurons and compared RiboMeth-seq data with non-targeting control ASO.
创建时间：
2025-03-18
