Normalized CT perfusion maps from 62 SAH patients

Aneurysmal subarachnoid hemorrhage (SAH) is a severe condition that triggers numerous metabolic disruptions and complications. While the exact mechanisms implied in this cascade of events are still being investigated, monitoring cerebral perfusion seems critical to understand and prevent the occurrence of secondary deficits such as delayed cerebral ischemia (DCI). The present dataset was built within the framework of a retrospective observational study in SAH patients. Sixty-two patients were included. Clinical information at admission, aneurysm details, neurological events, and rescue treatments were collected. Of note, within this study population, 33% of patients were classified as WFNS III-V. Cerebral vasospasm (CVS) occurrence was 68%, and that of DCI was 15%. Overall, 873 CT perfusion parametric maps (TMAX, MTT, CBF) were collected and preprocessed. In particular, all data were normalized to the MNI (Montreal Neurological Institute) standardized space that allows precise within an..., , , # Normalized CT perfusion maps from 62 SAH patients [https://doi.org/10.5061/dryad.0zpc86784](https://doi.org/10.5061/dryad.0zpc86784) #### CONTRIBUTORS: -Alexandre Kobbai -Quentin Mesnildrey (corresponding author: [[e-mail]](mailto:[e-mail])) -Vivien Szabo -Kévin Chalard #### RESEARCH SCOPE: Evolution of cerebral perfusion in patients diagnosed with aneurysmal subarachnoid hemorrhage. #### Description of the data and file structure This dataset includes: 873 preprocessed CT perfusion maps (TMAX, CBF, MTT) acquired in 62 patients diagnosed with aSAH. Data were initially acquired using GE Medical Systems device (24-slice scanner, GE Healthcare, Milwaukee, Wisconsin) with a slice thickness of 5mm. Parametric maps were computed using Perfusion_4D software (General Electric, revo_ct_22bc.50). The basilar artery was manually selected as the arterial input function and the venous outflow was automatically determined by the..., The present dataset does not contain any patient-related information. Subject identifiers are arbitrary; name, sex, and date of exam were removed from the metadata. Exam dates provided in the CTP_exam_dates.json file represent the delay relative to the initial SAH symptoms. All data were acquired in accordance with French ethics and regulations regarding patients' information, consent, data curation, and publication.动脉瘤性蛛网膜下腔出血（Aneurysmal subarachnoid hemorrhage, SAH）是一种可引发多种代谢紊乱与并发症的危重病症。尽管这一系列病理级联反应的确切机制仍在研究之中，但对脑灌注进行监测似乎是理解并预防迟发性脑缺血（Delayed Cerebral Ischemia, DCI）等继发性神经功能缺损的关键环节。 本数据集基于一项针对SAH患者的回顾性观察研究构建而成。 本研究共纳入62例患者，收集了其入院时的临床资料、动脉瘤细节、神经事件及急救治疗信息。值得注意的是，本研究队列中33%的患者被归为世界神经外科联合会（World Federation of Neurosurgical Societies, WFNS）Ⅲ~Ⅴ级；脑血管痉挛（Cerebral vasospasm, CVS）发生率为68%，迟发性脑缺血（DCI）发生率为15%。 最终共收集并预处理了873幅CT灌注参数图（TMAX、MTT、CBF），所有数据均被标准化至MNI（蒙特利尔神经科学研究所，Montreal Neurological Institute）标准空间，以实现精准的...（原文此处截断）。# 62例SAH患者的标准化CT灌注图谱 [https://doi.org/10.5061/dryad.0zpc86784](https://doi.org/10.5061/dryad.0zpc86784) #### 贡献者： - Alexandre Kobbai - 康坦·梅尼德里（Quentin Mesnildrey），通讯作者：[[e-mail]](mailto:[e-mail]) - Vivien Szabo - 凯文·沙拉尔（Kévin Chalard） #### 研究范围： 确诊动脉瘤性蛛网膜下腔出血患者的脑灌注动态变化。 #### 数据与文件结构说明： 本数据集包含：62例确诊动脉瘤性蛛网膜下腔出血患者的873幅预处理CT灌注参数图（TMAX、CBF、MTT）。 数据最初采用通用电气医疗系统（GE Medical Systems）的24层扫描仪（GE Healthcare，威斯康星州密尔沃基市）采集，层厚为5mm。 参数图采用Perfusion_4D软件（通用电气，版本revo_ct_22bc.50）计算生成，基底动脉被手动选为动脉输入函数，静脉流出量由...自动确定（原文此处截断）。本数据集不包含任何患者相关的个人信息，受试者标识符均为随机生成；元数据中已移除患者姓名、性别及检查日期。CTP_exam_dates.json文件中提供的检查日期为相对于初始SAH症状发作的时间延迟。所有数据的采集均符合法国关于患者信息、知情同意、数据管理及出版的伦理与法规要求。