The functions of innate lymphoid cells (ILCs) in immune system are increasingly appreciated, whereas the early development of ILCs in human remains elusive. In this study, we sorted humanhematopoietic
Plasmacytoid and conventional dendritic cells (pDC and cDC) are generated from progenitor cells in the bone marrow and it was shown that commitment to pDCs or cDC subtypes may occur in earlier and lat
T cells develop in the thymus from multipotent lymphoid precursors. During this gradual differentiation process thymocytes go through several decision points, before they fully mature into conventiona
Thetis cells (TCs), a recently identified family of RORgt+ antigen-presenting cells (APCs), comprise four subsets, including the TC IV subset that instructs tolerance to gut microbiota and food antige
