Derived single-cell data for: proliferative heterogeneity within tumour-infiltrating exhausted CD8⁺ T cells across a pan-cancer single-cell atlas
收藏资源简介:
Derived data accompanying the manuscript on proliferative heterogeneity within tumour-infiltrating exhausted CD8⁺ T cells. Contains the files needed to reconstruct the two integrated Seurat objects on which every reported analysis was performed, without redistributing the primary count matrices. CD8_Full_reconstruction.zip — scVI latent embedding, UMAP coordinates, cell metadata, barcodes and features for the full atlas (398,033 CD8⁺ T cells, 114 patients, 13 cancer contexts, four tissue compartments). CD8_TumourOnly_reconstruction.zip — the same five files for the tumour-only object (210,335 cells). Raw counts are not included; they are public under the accessions below. scVI integration is stochastic, so these embeddings are what allow the published figures to be reproduced exactly rather than approximately. Reconstruction scripts are in the accompanying code archive. Accessions: GSE138720, GSE156728, GSE193371, GSE254249, GSE120926, GSE319709 (atlas); GSE301720 (spatial).



