The crystal structure of N828V variant of DNA Pol Epsilon containing UTP in the polymerase active site
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The crystal structure of N828V variant of DNA Pol Epsilon containing UTP in the polymerase active site Descriptor: CALCIUM ION, DNA polymerase epsilon catalytic subunit A, GLYCEROL, ... Authors: Parkash, V, Johansson, E. Deposit date: 2022-09-29 Release date: 2023-10-25 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides. Nucleic Acids Res., 2023
DNA聚合酶ε(DNA polymerase epsilon)N828V变体的晶体结构,其聚合酶活性位点包含UTP。描述项:钙离子(CALCIUM ION)、DNA聚合酶ε催化亚基A(DNA polymerase epsilon catalytic subunit A)、甘油(GLYCEROL)等。作者:Parkash, V、Johansson, E. 提交日期:2022-09-29 发布日期:2023-10-25 最后修改日期:2026-03-04 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.6埃(2.6 Å)。引用文献:当DNA聚合酶ε区分核糖核苷酸时,传感器可辅助空间位阻门控。《核酸研究》(Nucleic Acids Res.),2023年



