Additional file 1: of The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells
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Sheet 1: Summery of acquired genomic alterations being selected for during docetaxel exposure in the MCF-7 sub-lines. Sheet 2: Details on the acquired genomic alterations being selected for during docetaxel exposure in the MCF-7 sub-lines. Positions are annotated with Ensembl VEP (version 2.8). The stage (sub-line) in which the alteration was acquired is given along with assigned variant class. Sheet 3: Same as sheet 2, but showing only Class A variation. Sheet 4: Same as sheet 3, but showing only the ‘most severe’ variant per gene. Sheet 5: Summery of acquired genomic alterations being selected for during docetaxel exposure in the MDA-MB-231 sub-lines. Sheet 6: Details on the acquired genomic alterations being selected for during docetaxel exposure in the MDA-MB-231 sub-lines. Positions are annotated with Ensembl VEP (version 2.8). The stage (sub-line) in which the alteration was acquired is given along with assigned variant class. Sheet 7: Same as sheet 6, but showing only Class A variation. Sheet 8: Same as sheet 7, but showing only the ‘most severe’ variant per gene. (XLSX 1113 kb)



