The ER-stress response and in particular the maladaptive and cell-death-promoting transcription factor CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) have been linked with diabetic kidney di
Altered expression of c-myc is implicated in pathogenesis and progression of many human cancers. Triple helix-forming oligonucleotides (TFOs) directed to a polypurine/polypyrimidine sequence in a crit
The chromatins are folded into three-dimensional (3D) structures inside cells, which coordinates the regulation of gene transcription by the non-coding regulatory elements. Aberrant chromatin 3D foldi
