The California Teachers Study (CTS) is a prospective observational cohort of N=133,477 adult women who have been followed since 1995. Participants completed up to six surveys and have been linked with
€,¥,§The frequency of DRB1 genotypes in ACPA subgroups was calculated as the number of ACPA-positive or ACPA-negative rheumatoid arthritis(RA) cases for a specific DRB1 allele (DRB1*04 +)divided by th