Identification of Driver Mutations for Induction of Pancreatic Cancer from Adult Tree Shrew (Tupaia belangeri chinensis) Acinar Cells

To investigate gene expression in the tree shrew pancreatic cancer model, tumor samples were analyzed by RNA-seq and the expression profiles were compared to those of human pancreatic cancer samples (n = 30) containing KRAS, TP53, and CDKN2A/B mutations downloaded from The Cancer Genome Atlas (https://tcga-data.nci.nih.gov/) and mouse pancreatic cancer (accession no. GSE87388), which showed similar histological features Overall design: comparation of gene expression profile among human, mouse and tree shrew pancreatic cancer. This series contains only tree shrew samples. Processed data are not available for this series because acceptable data with publicly trackable gene IDs or associated sequence were not provided.