首页/数据集/Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition

Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition

ChEBI2025-03-28 更新2026-07-12 收录

结直肠癌靶向治疗

分子信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-14877 数据链接链接失效反馈

官方服务：

资源简介：

Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition

应用场景：

创建时间：

2025-03-28

干细胞生物学

分子信号通路

Objective: Tissue stem cells are central regulators of organ homeostasis. We looked for a protein that is exclusively expressed and functionally involved in stem cell activity in rapidly proliferatin

干细胞与再生医学数据中心2022-02-20 更新80

Study of Bevacizumab Plus Chemotherapy in Patients With Metastatic Colorectal Cancer

生物标志物预测

结直肠癌靶向治疗

This study evaluates the relationship of biomarker expression and efficacy of bevacizumab plus chemotherapy in patients with unresectable/metastatic colorectal cancer. Before the treatment, the invest

NIAID Data Ecosystem60

Supplementary Table 10_Pro metastatic pathways identified by classification analysis from A Rare Subset of Primary Tumor Cells with Concomitant Hyperactivation of Extracellular Matrix Remodeling and dsRNA-IFN1 Signaling Metastasizes in Breast Cancer

癌症转移机制

分子信号通路

Supplementary Table reporting the Pro metastatic pathways identified by classification analysis

NIAID Data Ecosystem30

Colorectal Cancer (CRC) Cetuximab Elderly Frail

结直肠癌靶向治疗

老年肿瘤临床试验

OBJECTIVE: The principal objective of the trial is to evaluate whether the addition of cetuximab associated with 5-fluorouracil in elderly patients with KRAS wild type advanced colorectal cancer (CRC)

NIAID Data Ecosystem70

Design and Synthesis of a 2‑Amino-pyridine Derivative as a Potent CDK8 Inhibitor for Anti-colorectal Cancer Therapy

CDK8抑制剂

结直肠癌靶向治疗

CDK8 is a transcriptional cyclin-dependent kinase and considered as a potential target in colon cancer therapeutics. Here, a novel selective CDK8 inhibitor was identified against colon cancer in vivo.

Figshare60

Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition

资源简介：

相关数据集