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Direct Synthesis of a Dioxabenzobicyclo[3.2.1]octane Core from Salicylaldehydes

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Figshare2018-10-01 更新2026-04-29 收录
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A copper­(II) trifluoromethanesulfonate via Prins reaction between salicylaldehydes and allyl alcohols is realized under mild conditions. A series of compounds containing dioxabenzobicyclo[3.2.1]­octane motifs are obtained in moderate to good yields. The current method can efficiently construct the valuable structural motif from easily accessed starting materials, providing a smooth method to build benzobicyclo skeletons.

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2018-10-01
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