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Highly Enantioselective Friedel−Crafts Alkylations of Pyrroles and Indoles with α‘-Hydroxy Enones under Cu(II)-Simple Bis(oxazoline) Catalysis

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Highly_Enantioselective_Friedel_Crafts_Alkylations_of_Pyrroles_and_Indoles_with_Hydroxy_Enones_under_Cu_II_Simple_Bis_oxazoline_Catalysis/3293797
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Remarkably high and regular enantioselectivities are obtained in Friedel−Crafts alkylation reactions involving α‘-hydroxy enone templates and Cu(II)−bis(oxazoline) complexes as catalysts. The simple elaboration of adducts provides a route to enantioenriched aldehydes, carboxylic acids, and ketones containing the pyrrole and indole frameworks.
创建时间:
2016-05-06
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