A Product of a Templated Solid-State Photodimerization Acts as a Template: Single-Crystal Reactivity in a Single Polymorph of a Cocrystal

The concept of using a product of a template-directed solid-state reaction as a template is demonstrated. A cyclobutane lined with four carboxylic acid groups is employed as the template in photoreactive cocrystals. The resulting material is shown to exhibit polymorphism.