Single-nucleus sequencing of liver cells from hepatocyte-specific Nampt knockout mice and WT littermates reveals major changes to the hepatocyte transcriptome in mice with necrosis

NIAID Data Ecosystem2026-03-13 收录

肝细胞特异性Nampt敲除

坏死转录组分析

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE174234 数据链接链接失效反馈

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资源简介：

Single-nucleus RNAseq was performed to investigate whether transcriptomics changes observed in bulk RNAseq could be attributed to specific hepatic cell populations. We isolated nuclei from 3 hepatocyte-specific Nampt knockout (HNKO) mice and 3 WT littermates, and sequenced 4,250 nuclei/sample

创建时间：

2022-02-08

Single-nucleus sequencing of liver cells from hepatocyte-specific Nampt knockout mice and WT littermates reveals major changes to the hepatocyte transcriptome in mice with necrosis

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