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Effect of combined AURK and BCL2 inhibition on gene expression in double-hit lymphoma xenografted mice

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NIAID Data Ecosystem2026-05-02 收录
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To investigate the mechanism behind drug synergism between MLN8237 and venetoclax we injected DoHH2 human tumor cells into SCID mice SQ, treated animals for 3 days, and harvested tumors for RNAseq. Comparative gene expression profile analysis of RNA-seq data for DoHH2 tumors harvested from mice, treated with either vehicle, MLN8237, venetoclax, or combination MLN8237 + venetoclax for 3 days

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2025-06-25
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