Cellular senescence is an irreversible cell growth arrest state linked to loss of tissue function and aging in mammals. The cellular transition from proliferation to senescence is marked by increased

干细胞与再生医学数据中心2022-02-20 更新130

Towards understanding the biological drivers of cellular ageing

细胞衰老

蛋白质组学

Human ageing is associated with gradual loss of tissue and organ function, with consequent frailty and illness leading to poor quality of later life for many older people. It is thought to result from

CESSDA2025-06-12 更新80

TCA cycle in senescence

TCA循环

细胞衰老

Pyruvate dehydrogenase (PDH) is a central enzyme in relation to the TCA cycle, as it converts pyruvate into acetyl-CoA. Its activity favours TCA cycle activity. PDH is downregulated by PDH kinase (PDK

wikipathways.github.io150

Set 1_S1_molecule

肾脏疾病

细胞衰老

Renal artery stenosis (RAS) engenders stenotic-kidney ischemia, dysfunction, and injury, but whether these are mediated by cellular senescence has not been elucidated. Using INK-ATTAC transgenic mice,

DataCite Commons2020-09-24 更新80

Transcription-driven cohesin accumulation is associated with secretory phenotype of senescence

资源简介：

相关数据集