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Asymmetric Hydrogenation of Ketones Using a Ruthenium(II) Catalyst Containing BINOL-Derived Monodonor Phosphorus-Donor Ligands

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Asymmetric_Hydrogenation_of_Ketones_Using_a_Ruthenium_II_Catalyst_Containing_BINOL_Derived_Monodonor_Phosphorus_Donor_Ligands/3318721
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A series of ruthenium(II) complexes containing BINOL-based monodonor phosphorus ligands have been prepared and applied to the asymmetric catalysis of the hydrogenation of aryl/alkyl ketones. The best ligands for this application are those which contain an aromatic groups with either a methoxide or bromide on the ortho position. Using these ligands, alcohols with ee's of up to 99% are formed.
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2016-05-06
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