Efficacy and safety of oral propranolol versus topical timolol maleate in the treatment of large superficial infantile hemangiomas: a randomized controlled trial

To compare the efficacy of topical timolol maleate and oral propranolol in the treatment of large superficial infantile hemangioma through a randomized controlled trial, providing evidence-based treatment decisions for large superficial infantile hemangioma evidence.

本研究通过随机对照试验（randomized controlled trial），比较外用马来酸噻吗洛尔（topical timolol maleate）与口服普萘洛尔（oral propranolol）治疗大型浅表型婴幼儿血管瘤（infantile hemangioma）的临床疗效，旨在为大型浅表型婴幼儿血管瘤的治疗提供循证决策依据。