Effects of mean steps/day, body mass index (BMI) and waist-hip ratio (WHR) on the association between type 2 diabetes mellitus (T2D) and total hippocampal volume (n = 532).

*p<0.05 ^p<0.01. Model 1 –association between T2D and total hippocampal volume. Model 2 –model 1 adjusted additionally for mean steps/day. Model 3 –model 2 adjusted additionally for BMI. Model 4 –model 3 adjusted additionally for WHR. β–beta coefficient, CI–confidence interval, T2D –type 2 diabetes mellitus, BMI–body mass index, WHR–waist-hip ratio. All models adjusted for age, sex, years of education, total intracranial volume, vascular risk (hypertension and/or hyperlipidemia and/or smoking and/or history of stroke and/or history of ischemic heart disease), apolipoprotein ε4 allele and Geriatric Depression Scale score.