Figure 3

Fig. 3 Increased amyloidosis in young male 5xFAD mice
overexpressing Hsp90 co-chaperone STI1. Sheet 1 b quantification of average area
fraction (% area) of Congo Red staining across the whole hippocampus in
3-5-month-old male 5xFAD and TgA-5xFAD mice. Sheet 2 d quantification of
average percent area of the whole hippocampus with Thioflavin S staining. Sheet 3 f
quantification of average percent area across the whole hippocampus with Aβ
immunofluorescence. Concentration (ng/mg) of Tris Soluble (Sheet 4) g, and
Guanidinium hydrochloride Insoluble h (Sheet 5), Human Aβ1-42 in
cortex (1 hemisphere) from 3-5-month old 5xFAD and TgA-5xFAD male mice.