The p53RE-related sequence that is predicted to have the greatest function in the promoter regions (±5 kb from transcription start site) of human <i>TLR</i> genes.

In lower case characters are the mismatches relative to the consensus p53 response element (RE). The bold characters are half-site p53REs without mismatches relative to the consensus p53 RE. The italic lower case characters correspond to the spacer sequence between p53 decamers. A lack of spacer between decamer sequences is denoted by “-”. ∧ Indicates that the predicted RE contains a single nucleotide polymorphism (SNP). SNPs are indicated in bold and underline characters. TLR5 SNP rs2192617 C/T TLR6 SNP rs167251 G/A TLR8 SNP rs3761624 A/G *Number of noncanonical p53 REs is indicated inside the parenthesis. **Chromosome coordinates based on USC Genome Browser Human Feb. 2009 (GRCh37/hg19) http://genome.ucsc.edu/.