FAD attaches to SDHA
收藏reactome.org2025-01-15 收录
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Flavin adenine dinucleotide (FAD) binds covalently and non-enzymatically to succinate dehydrogenase complex II (SDH) subunit A (SDHA). The exact mechanism is unclear but depends on the presence of succinate dehydrogenase assembly factor 2 (SDHAF2, SDA5). Fumarate enhances the process (Hao et al., 2009; Maklashina et al., 2022).
黄素腺嘌呤二核苷酸（FAD）以共价和非酶促方式与琥珀酸脱氢酶复合物II（SDH）亚基A（SDHA）结合。其确切机制尚不明确，但依赖于琥珀酸脱氢酶组装因子2（SDHAF2，SDA5）的存在。富马酸可增强此过程（Hao et al., 2009；Maklashina et al., 2022）。
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