A practical approach to febrile cancer patients: Diagnostic stewardship in Oncology units

INTRODUCTION: Cancer and cytotoxic chemotherapy used for its treatment predispose to severe and often fatal infections. Prompt diagnosis and timely antibiotic therapy is crucial, with delays in initiating therapy having high mortality. Complete blood counts (CBC) are an inexpensive, standardized, preliminary investigation for management and follow-up of cancer patients with diagnostic and prognostic value. METHOD: To study the types of infections associated with various cancers on chemotherapy, their etiologies and susceptibility patterns, and the hematological profile of these patients as predictors of infection. RESULTS: A total of 21 patients (12 solid and 9 hematological malignancies) presented with 31 febrile episodes. WBC count (2079 cells/cu.mm), percentage of neutrophils (52.9%), absolute neutrophil (137.5 cells/cu.mm) and platelet counts (1,77,507 cells/cu.mm) were significantly lower in the 11 febrile neutropenic patients. Absolute lymphocyte count (412.7 cells/cu.mm) was redu..., , , GENERAL INFORMATION 1. Title of Dataset: A practical approach to febrile cancer patients: Diagnostic stewardship in Oncology units 2. Author Information:Authors: Sridevi H.B., Anisha Maria Fernandes, Sanyo D'souza, Prashantha B., Pooja Rao, Suchitra Shenoy M. 3. Duration of data collection (single date, range, approximate date):12 months (Aug 2021- July 2022) 4. Geographic location of data collection: Mangalore, Karnataka, India 5. Information about funding sources that supported the collection of the data: Nil SHARING/ACCESS INFORMATION 1. Licenses/restrictions placed on the data: Nil 2. Links to publications that cite or use the data: Nil 3. Links to other publicly accessible locations of the data: Nil 4. Links/relationships to ancillary data sets: Nil 5. Was data derived from another source? no A. If yes, list source(s): 6. Recommended citation for this dataset:Â H.B., Sridevi et al. (2024). A practical approach to febrile cancer patients: Diagnostic stewardship in Oncology...【研究背景】癌症及其治疗所用的细胞毒性化疗方案，会使患者易罹患严重乃至致命的感染。快速诊断与及时抗菌治疗至关重要，治疗启动延迟会显著升高患者死亡率。全血细胞计数（Complete Blood Counts, CBC）是一种低成本、标准化的初步检测手段，用于癌症患者的诊疗管理与随访，兼具诊断与预后价值。 【研究方法】本研究旨在探讨接受化疗的各类癌症患者所伴发的感染类型、病原体及其药敏模式，并分析此类患者的血液学特征，以作为感染发生的预测指标。 【研究结果】本研究共纳入21例患者（其中12例为实体瘤患者，9例为血液系统恶性肿瘤患者），共计发生31次发热事件。在11例发热性中性粒细胞减少症患者中，白细胞计数（2079个/立方毫米）、中性粒细胞占比（52.9%）、中性粒细胞绝对计数（137.5个/立方毫米）以及血小板计数（177507个/立方毫米）均显著降低。淋巴细胞绝对计数（412.7个/立方毫米）呈降低趋势…… 【基本信息】 1. 数据集标题：发热癌症患者的临床实践路径：肿瘤科室的诊断管控 2. 作者信息：作者：Sridevi H.B.、Anisha Maria Fernandes、Sanyo D'souza、Prashantha B.、Pooja Rao、Suchitra Shenoy M. 3. 数据收集时长：12个月（2021年8月—2022年7月） 4. 数据收集地点：印度卡纳塔克邦芒格洛尔市 5. 数据资助来源：无 【数据共享与获取信息】 1. 数据使用许可与限制：无 2. 引用该数据集的文献链接：无 3. 该数据集的其他公开访问链接：无 4. 附属数据集关联信息：无 5. 本数据集是否源自其他来源？否 A. 若是，请列出来源： 6. 数据集推荐引用格式：H.B. Sridevi 等（2024）. 发热癌症患者的临床实践路径：肿瘤科室的诊断管控……