Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats (Femur - microCT, three-point bending, histomorphometry)

Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of...骨骼载荷减少可引发显著的骨量丢失。后肢悬吊（hindlimb suspension）动物模型已被广泛应用于评估骨骼在……过程中的变化。