Changes in the properties of neural progenitor cells due to Shh signaling and treatment time

NIAID Data Ecosystem2026-05-02 收录

神经细胞分化

Shh信号通路抑制

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https://www.ncbi.nlm.nih.gov/sra/DRP011952 数据链接链接失效反馈

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Different concentrations of sonic hedgehog protein were treated onto chick neural progenitor cells, and the concentration- and time-dependent changes in properties were detected by a gene expression analysis.

创建时间：

2024-08-30

Supplementary Figure 1

细胞培养

神经细胞分化

It comprises of raw data and analysis file of Supplementary Figure 1 obtained by determining the effect of L929 conditioned medium on PC12 cell differentiation. PC12 cells were treated with naive medi

DataCite Commons2023-03-28 更新90

Effect of recombinant Shh on gene expression of primary rat nucleus pulposus cells

浆细胞转录组学

Shh信号通路抑制

In order to study the effect of recombinant Shh (rShh) on nucleus pulposus cells, primary nucleus pulposus cells from SD rats were obtained.Then, nucleus pulposus cells were treated with rShh at 200 n

NIAID Data Ecosystem50

Effect of externally applied concave and convex curvature for 24 hours with continued duam SMAD inhibition (dSMADi) on human embryonic cell line H9 after 48 hours of dSMADi induction to attain early neuroepithelial features. Effect of externally applied concave and convex curvature for 24 hours with continued duam SMAD inhibition (dSMADi) on human embryonic cell line H9 after 48 hours of dSMADi induction to attain early neuroepithelial features

神经细胞分化

生物力学响应

To investigate the transcriptional change induced by externally applied concave and convex curvature, the former of which displayed tissue-level morphological change, human embryonic cell line H9 main

NIAID Data Ecosystem30

Finding genomic targets of transcription factor Six3 in neural stem cells.. Finding genomic targets of transcription factor Six3 in neural stem cells.

转录因子靶点

神经细胞分化

Pro-neural transcription factor Six3 has been implicated in neuronal differentiation. We established primary neural stem cell with Six3 overexpression, and utilized CUT&RUN to profile genomic loci bou

NIAID Data Ecosystem50

Supplementary Tables: Designing signaling environments to modulate neural progenitor cell differentiation with regulatory network models

神经细胞分化

信号建模

During development, progenitors integrate external signaling cues to control differentiation. How combinatorial signal inputs modulate fate decisions and the underlying molecular information processin

CaltechDATA2025-09-19 更新30

Changes in the properties of neural progenitor cells due to Shh signaling and treatment time

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