ARID1A plays an important role in skin inflammation.

NIAID Data Ecosystem2026-05-01 收录

皮肤炎症机制

ARID1A敲低转录组

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE231593 数据链接链接失效反馈

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资源简介：

Loss of ARID1A reduced the inflammatory gene expression of human keratinocytes treated with POLY IC ARID1A knockdown RNA-Seq in polyIC induced primary human keratinocytes.

创建时间：

2023-05-08

Hypoxia inhibits TNF-α-induced TSLP expression in keratinocytes

皮肤炎症机制

缺氧信号通路

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TIMP3, a CLOCK-controlled gene, determines cell susceptibility to UV-induced expression of inflammatory factors in human keratinocytes.

皮肤炎症机制

生物钟基因调控

To search for CLOCK-controlled genes in human keratinocytes, we introduced siRNAs against CLOCK and harvested the cells at two time points, ZT 32 and 44. We speculated that those genes that were downr

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mRNA sequencing of skins isolated from B6;129S4-Npytm2Rpa/J homozygous mice and wildtype litter mates reveals transcriptomic changes indicative of skin inflammation associated with Npy overexpression.

皮肤炎症机制

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Neuropeptide Y (NPY) is a pleiotropic peptide produced in the central nervous system and peripheral organs. Despite conjectures that NPY may have a role in skin physiology and pathology, the effects o

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Comparing transcriptional profiles of skin biopsies from healthy controls and subjects with chronic pruritus of unknown origin and atopic dermatitis

皮肤转录组学

皮肤炎症机制

Type 2 inflammation contributes to the pathology of pruritic skin diseases such as atopic dermatitis (AD). Chronic pruritus of unknown origin (CPUO) is a skin condition of unknown etiology that typica

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DataSheet_1_A Murine Point Mutation of Sgpl1 Skin Is Enriched With Vγ6 IL17-Producing Cell and Revealed With Hyperpigmentation After Imiquimod Treatment.csv

皮肤炎症机制

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Sphingosine-1-phosphate lyase is encoded by the Sgpl1 gene, degrades S1P, and is crucial for S1P homeostasis in animal models and humans. S1P lyase deficient patients suffer from adrenal insufficiency

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ARID1A plays an important role in skin inflammation.

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