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Identification of new classes of antimalarial compounds by targeting Single-Stranded DNA binding protein of Plasmodium falciparum

Mendeley Data2024-06-07 更新2024-06-26 收录

抗疟药物发现

靶向药物研发

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This data contains supplementary tables and figures

本数据集包含补充表格与插图

应用场景：

创建时间：

2024-06-05

靶向药物研发

计算化学筛选

The human receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a critical necroptosis regulator implicated in cancer, psoriasis, ulcerative colitis, rheumatoid arthritis, Alzheimer’s dise

Figshare2022-08-08 更新110

Plasmodium falciparum thymidylate kinase in complex with a urea-alpha- deoxythymidine inhibitor

抗疟药物发现

结构生物学

Plasmodium falciparum thymidylate kinase in complex with a urea-alpha- deoxythymidine inhibitor Descriptor: 1-[[(2R,3S,5S)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]meth

Protein Data Bank Japan2023-12-20 更新60

S100A9 Overexpression Drives Chemoresistance and Poor Prognosis in AML with Adavivint as a Targeted Therapeutic

急性髓系白血病

靶向药物研发

Drug resistance and poor prognosis in acute myeloid leukemia (AML) are major challenges, underscoring the need for effective biomarkers and targeted therapies. In this study, we identified S100A9 as a

NIAID Data Ecosystem60

Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12

补体系统结构生物学

靶向药物研发

Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 Descriptor: CITRIC ACID, Complement factor D, Fab20D12 Light Chain, ... Authors: Wu, P, Harris, S.F, Eigenbrot, C. Deposit d

Protein Data Bank Japan2024-10-16 更新80

Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST

靶向药物研发

cKIT抑制剂

Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST Descriptor: 5-imidazo[1,2-a]pyridin-3-yl-~{N}-[(1~{R})-1-(6-pyrrolidin-1-ylpyridin-

Protein Data Bank Japan2024-02-07 更新60

Identification of new classes of antimalarial compounds by targeting Single-Stranded DNA binding protein of Plasmodium falciparum

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