Supplemental Table S3 from Clonal Hematopoiesis in Young Women Treated for Breast Cancer
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CHIP Mutations Identified in One-Year Samples
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2023-07-05
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DNA sequencing of human blood sample for Clonal Hematopoiesis of Indeterminate Potential (CHIP) detection.. DNA sequencing of human blood sample for Clonal Hematopoiesis of Indeterminate Potential (CHIP) detection.
The present study aimed to gain insights into the pathological process of Calcific Aortic Valve Disease (CAVD) in CHIP carriers. To this end, we screened for CHIP, by DNA sequencing of blood samples,
NIAID Data Ecosystem30
Tables S2, S7, S8, S9 from Dynamics of Age- versus Therapy-Related Clonal Hematopoiesis in Long-term Survivors of Pediatric Cancer
Table S2: List of CH mutations identified. Table S7: Mutations analyzed in serial analysis. Table S8: Clinical features of the survivors. Table S9: List of primers used in ddPCR validation.
Figshare2023-04-03 更新10
Inflammatory signals from fatty bone marrow support DNMT3a-driven clonal hematopoiesis (NOD/SCID/IL-2Rgc-null subset). Inflammatory signals from fatty bone marrow support DNMT3a-driven clonal hematopoiesis (NOD/SCID/IL-2Rgc-null subset)
Accumulation of fatty bone marrow (FBM) is one of the key age related changes possibly influencing the blood system. While a link between obesity and cancer evolution has been reported it remains unkn
NIAID Data Ecosystem10
CDK4/6 inhibition mitigates chemotherapy-induced expansion of TP53-mutant clonal hematopoiesis
Therapy-related myeloid neoplasms (tMN) represent a fatal consequence of exposure to cytotoxic therapy administered in the treatment of cancer. Individuals with pre-existing TP53 clonal hematopoiesis
NIAID Data Ecosystem20
IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cells. IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cells
JAK2-V617F is the most frequent somatic mutation causing myeloproliferative neoplasm (MPN). JAK2-V617F can be found in healthy individuals with clonal hematopoiesis of indeterminate potential (CHIP) w
NIAID Data Ecosystem10
