Quantification of fold change in hippocampal and cortical transcript levels in 3xTgAD mice compared age-matched WT.

*P**P***PPooled data from 9–18 month old mice: n = 25 to AD; n = 38 to WT; n.d., not detectable. HPC, hippocampus; CX, cortex.1Gfap-Δ135 and Gfap-dEx6 assays lack sensitivity to detect levels lower than 0.003% of Gfap-α.2Gfap-ΔEx7 was not detectable in all of the samples; indicated number of mice (TG+WT) with detectable signal over all mice studied. No change in AD vs WT was detected.Data are presented as fold change of 3xTgAD mice compared to expression levels found in WT mice of the same age.