Gene regulation in hematopoietic cells by Pcgf1 in a Runx1 null background

ChEBI2012-06-17 更新2026-07-21 收录

造血干细胞调控

表观遗传机制研究

数据链接：

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资源简介：

Gene regulation in hematopoietic cells by Pcgf1 in a Runx1 null background

创建时间：

2012-06-17

ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation

造血干细胞调控

转录因子功能分析

To investigate the role of the transcription factor ERG in hematopoiesis we generated Erg heterozygous knockout and conditional Erg knockout mice. We found that several hematopoietic cell types were d

NIAID Data Ecosystem60

In Vivo Analysis of Retroviral Enhancer Mutations in Hematopoietic Cells: SP1/EGR1 and ETS/GATA Motifs Contribute to Long Terminal Repeat Specificity

造血干细胞调控

逆转录病毒增强子功能

The objective of this work was to identify, in the context of chromosomally integrated DNA, the contribution of defined transcription factor binding motifs to the function of a complex retrovirus enha

PubMed Central40

A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia [amplicon-seq]

造血干细胞调控

白血病分子机制

we uncover a key transcriptional network involving hundreds of genes that is required for HSC self-renewal. Overall design: MECOM impact on the hematopoietic stem cells

NIAID Data Ecosystem20

DNA Polymerase Delta Governs Parental Histone Transfer to DNA Replication Lagging Strand

DNA复制偶联组蛋白回收

表观遗传机制研究

Chromatin replication is intricately intertwined with DNA replication, and the recycling of parental histones is essential for epigenetic inheritance. The transfer of parental histones to both the DNA

NIAID Data Ecosystem40

Musashi 2 is a regulator of the hematopoietic stem cell compartment identified by a retroviral insertion screen and knockout mice

造血干细胞调控

基因功能研究

Musashi 2 is a regulator of the hematopoietic stem cell compartment identified by a retroviral insertion screen and knockout mice

ChEBI2011-05-21 更新20