Kinome expression profiling of muscle invasive bladder cancer (MIBC) patients

Muscle invasive bladder cancer (MIBC) is one of the aggressive cancer with limited treatment options. Targeted gene expression profiling in normal and tumor samples from MIBC patients could aid in identification of potential therapeutic targets. Thus we used kinase specific panel to study their expression pattern and to identify targetable genes. Tumor and adjacent normal macrodissected tissues were obtained from 24 MIBC patients. RNA isolated from tissues were profiled on the nCounter Human Kinase Panel.